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    Government Action and Communication Institute (GACI) is a non-partisan 501(c)(3) public policy, education, and research organization specializing in health care, social services, and education issues.

    GACI’s mission is to bring the most relevant information - research, best practices, and model programs - to policy leaders and decision makers at the federal, state, and local levels. We use events to provide opportunities for government, academia, and business leaders to talk and work together.

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    Policy Insights 2015 California Budget Project Conference
    Wednesday, March 4, 2015
    8:30am – 4:30pm, Reception following Sacramento Convention Center, 3rd Floor
    S as well as to develop new treatments in guillain-barré syndrome. 1. Introduction in the 19th century, robert koch postulated a causal relationship between a pathogenic microbe and a disease [1]. This was later extended to the role of autoantibodies in the pathogenesis of human disease by witebsky et al. [2]. In 1957, they proposed the fulfillment of several criteria to proof the pathogenic effects of autoantibodies, namely, the direct demonstration of free, circulating, or cell-bound antibodies by indirect means, the recognition of specific antigen against which the antibody is directed, the production of antibodies against the same antigen in experimental animals and finally the appearance of pathological changes in the corresponding tissues of an actively sensitized experimental model that is similar to that in the human disease. Taking into account both koch’s and witebsky’s postulates, the term “molecular mimicry” was proposed as a mechanism by which infectious agents trigger an immune response against autoantigens, resulting in the development of autoimmune diseases. Similar criteria must be satisfied to conclude that a disease is triggered by molecular mimicry [3]. They are as follows: (i) the establishment of an epidemiological association between the infectious agent and the immune-mediated disease; (ii) the identification of t cells or antibodies directed against the patient’s target antigens; (iii) the identification of microbial mimics of the target antigen; (iv) reproduction of the disease in an animal model. Although there have been a number of diseases proposed to exhibit the mechanism of molecular mimicry, none has been proven in examples of human diseases based on fulfilment of all four criteria [4]. viagra cheap buy canada viagra without a doctor prescription generic viagra generic viagra online buy viagra online buy generic viagra viagra without a doctor prescription cheap generic viagra online pharmacy buy viagra from india viagra online Guillain-barré syndrome (gbs), characterized by limb weakness and areflexia, has become the most frequent cause of acute flaccid paralysis since the near elimination of poliomyelitis in the world [5]. Most gbs patients have had either gastrointestinal or upper respiratory symptoms one to three weeks prior to the onset of their neurological symptoms, making gbs the prototype of postinfectious autoimmune diseases. Gbs can be classified into two major subtypes, acute inflammatory demyelinating polyneuropathy (aidp) and acute motor axonal neuropathy (aman) depending on whether the myelin or the axonal components of the peripheral nerves are affected. Experimental autoimmune neuritis (ean) resembles aidp clinically and pathologically. Ean can be transferred to animals by t cells se.

    The SCAN Foundation 4th LTSS Summit
    Tuesday, September 30, 2014
    9:00am – 4:00pm – Reception following Sacramento Convention Center
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    Player's Guide to the Capitol: California Lawmakers.

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